This is a story about sports-broadcaster-turned-morning-talk-show-host Danny Tanner and his three little girls, D.J. (Donna Jo), Stephanie, and Michelle Tanner. Before the show begins, Danny Tanner's wife is killed by a drunk driver, so he needs help raising his daughters. He asks his rock-musician brother-in-law Jesse Katsopolis and his comedian best friend Joey Gladstone to move in with them. As the show goes on, Jesse marries Rebecca Donaldson, Danny's talk-show co-host, and they have twin sons, Nicholas Katsopolis.